Anti-rat monoclonal antibodies
A secondary monoclonal antibody binds with a primary antibody that is directly attached to the target antigen. Secondary monoclonal antibodies are more sensitive and flexible in labeling and detection and can be used for:
- ELISA,
- IH
- IC,
- DOT-ELISPOT,
- cryosection.
SYnAbs developed unique mouse monoclonal antibodies targeting the entire repertoire of rat species, so covering all rat isotypes. Our anti-rat secondary antibodies are protein A-purified monoclonal antibodies with well-characterized specificity for rat immunoglobulin classes.
They are available in mouse species and in the following formats:
- Unlabeled antibodies
- Enzyme conjugates (alkaline phosphatase (AP) or horseradish peroxidase (HRP))
- Fluorescent conjugates (Alexa Fluor, DyLight, Fluorescein (FITC), etc.)
- Biotin
IgG1 kappa Mouse anti-rat kappa light chain
Kappa light chain - MARK-1
Description : IgG1 kappa Mouse anti-rat kappa light chain
Class: monoclonal
Type: secondary
Antigen: rat kappa light chain
Host/Isotype : mouse/IgG1 kappa
Citations:
- A key role for TGF-beta signaling to T cells in the long-term acceptance of allografts
- Fc-disabled anti-mouse CD40L antibodies retain efficacy in promoting transplantation tolerance
- Eosinophilic bowel disease controlled by the BB rat-derived lymphopenia/Gimap5 gene
- Locally delivered CD40 agonist antibody accumulates in secondary lymphoid organs and eradicates experimental disseminated bladder cancer
- A rat monoclonal anti-(human CD2) and L-leucine methyl ester impacts on human/SCID mouse graft and B lymphoproliferative syndrome
- Prolongation of survival of guinea pig heart grafts in cobra venom factor-treated rats by splenectomy. No additional effect of cyclosporine.
- Lack of L-selectin expression by cells transferring diabetes in NOD mice: insights into the mechanisms involved in diabetes prevention by Mel-14 antibody treatment.
- Characterisation of rat anti-guinea pig circulating xenoreactive natural antibodies and secreting cells.
- Interdental supragingival plaque--a natural habitat of Actinobacillus actinomycetemcomitans, Bacteroides forsythus, Campylobacter rectus, and Prevotella nigrescens.
- In vivo depletion of xenoreactive natural antibodies with an anti-mu monoclonal antibody.
- Human immunoglobulin preparations for intravenous use prevent experimental autoimmune uveoretinitis.
- Anti-renin T cells trigger normal B cells to produce anti-renin antibodies and normalize blood pressure in spontaneously hypertensive rats
- Differentiation of membrane IgE+ rat B cells into IgE-secreting cells.
- HgC12 induces T and B cells to proliferate and differentiate in BN rats.
- Rat (and mouse) monoclonal antibodies. V. A simple automated technique of antigen purification by immunoaffinity chromatography.
- Purification of rat monoclonal antibodies.
- Fc gamma receptors on rat eosinophils: isotype-dependent cell activation.
- Rat monoclonal antibodies. IV. Easy method for in vitro production.
- Rat monoclonal antibodies. I. Rapid purification from in vitro culture supernatants.
IgG1 kappa Mouse anti-rat kappa light chain IgK-1a
Kappa light chain - MARK-3
Description : IgG1 kappa Mouse anti-rat kappa light chain IgK-1a
Class: monoclonal
Type: secondary
Antigen: rat kappa light chain
Host/Isotype : mouse/IgG1 kappa
|
Citations:
- Characterisation of rat anti-guinea pig circulating xenoreactive natural antibodies and secreting cells.
- A rapid and efficient purification method for horse IgG(T) using a rat monoclonal antibody.
- Differentiation of membrane IgE+ rat B cells into IgE-secreting cells.
- CD23 expression in aged rats.
- Rat (and mouse) monoclonal antibodies. V. A simple automated technique of antigen purification by immunoaffinity chromatography.
- Fc epsilon receptors on rat B-lymphocytes: specificity and binding kinetics.
- Rat monoclonal antibodies. II. A rapid and efficient method of purification from ascitic fluid or serum.
- Rat monoclonal antibodies. I. Rapid purification from in vitro culture supernatants.
IgG1 kappa Mouse anti-rat lambda light chain
Lambda light chain - MARL-15
Description : IgG1 kappa Mouse anti-rat lambda light chain
Class: monoclonal
Type: secondary
Antigen: rat lambda light chain
Host/Isotype : mouse/IgG1 kappa
Citations:
- A key role for TGF-beta signaling to T cells in the long-term acceptance of allografts
- Fc-disabled anti-mouse CD40L antibodies retain efficacy in promoting transplantation tolerance
- Eosinophilic bowel disease controlled by the BB rat-derived lymphopenia/Gimap5 gene
- Locally delivered CD40 agonist antibody accumulates in secondary lymphoid organs and eradicates experimental disseminated bladder cancer
- Characterisation of rat anti-guinea pig circulating xenoreactive natural antibodies and secreting cells.
IgG1 kappa Mouse anti-rat kappa & lambda light chain
Kappa & Lambda light chain - MARK(K+L)
Description : IgG1 kappa Mouse anti-rat kappa & lambda light chain
Class: monoclonal
Type: secondary
Antigen: rat kappa & lambda light chain
Host/Isotype : mouse/IgG1 kappa
IgG1 kappa Mouse anti-rat mu heavy chain
Mu heavy chain - MARM-4
Description : IgG1 kappa Mouse anti-rat mu heavy chain
Class: monoclonal
Type: secondary
Antigen: rat mu heavy chain
Host/Isotype : mouse/IgG1 kappa
Activity: depleting antibody, for in-vivo use
IgG1 kappa Mouse anti-rat mu heavy chain
Mu heavy chain - MARM-7
Description : IgG1 kappa Mouse anti-rat mu heavy chain
Class: monoclonal
Type: secondary
Antigen: rat mu heavy chain
Host/Isotype : mouse/IgG1 kappa
Activity: depleting antibody, for in-vivo use
Citations:
- Investigation of the role of tumour necrosis factor alpha, interleukin-1 beta, interleukin-10, nitric oxide and rheumatoid factor-immunoglobulin M in a rat model of arthritis
- Accommodation of vascularized xenografts: expression of "protective genes" by donor endothelial cells in a host Th2 cytokine environment
- Prolongation of survival of guinea pig heart grafts in cobra venom factor-treated rats by splenectomy. No additional effect of cyclosporine.
- Characterisation of rat anti-guinea pig circulating xenoreactive natural antibodies and secreting cells.
- Depletion of IgM xenoreactive natural antibodies by injection of anti-mu monoclonal antibodies.
- Use of anti-mu monoclonal antibody as a therapeutic approach to achieve depletion of xenoreactive natural antibodies.
- In vivo depletion of xenoreactive natural antibodies with an anti-mu monoclonal antibody.
- Anti-renin T cells trigger normal B cells to produce anti-renin antibodies and normalize blood pressure in spontaneously hypertensive rats.
- Differentiation of membrane IgE+ rat B cells into IgE-secreting cells.
- Isotype characterization of rat preformed natural antibodies against guinea pig cells.
- Failure to detect immune deficiency in rats after prenatal or early postnatal irradiation.
- Transplantable IgD immunoglobulin-secreting tumors in rat.
- Effect of chemical sympathectomy and pinealectomy upon gonads of voles (Microtus agrestis) exposed to short photoperiod.
- Three classes and four (sub)classes of rat immunoglobulins: IgM, IgA, IgE and IgG1, IgG2a, IgG2b, IgG2c.
- Modulation of rat B cell differentiation in vivo by the administration of an anti-mu monoclonal antibody
IgG1 kappa Mouse anti-rat delta heavy chain
Delta heavy chain - MARD-3
Description : IgG1 kappa Mouse anti-rat delta heavy chain
Class: monoclonal
Type: secondary
Antigen: rat delta heavy chain
Host/Isotype : mouse/IgG1 kappa
Activity: depleting antibody, for in-vivo use
Citations:
- Characterisation of rat anti-guinea pig circulating xenoreactive natural antibodies and secreting cells.
- Depletion of IgM xenoreactive natural antibodies by injection of anti-mu monoclonal antibodies.
- Differentiation of membrane IgE+ rat B cells into IgE-secreting cells.
- CD23 expression in aged rats.
- IgG2b or IgE molecules can be co-expressed with those of the IgM and IgD isotypes of the membrane of normal rat B cells.
- In vivo kinetics and nature of rat IgE-bearing lymphocytes after IgE stimulation.
IgG1 kappa Mouse anti-rat alpha heavy chain
Alpha heavy chain - MARA-1
Description : IgG1 kappa Mouse anti-rat alpha heavy chain
Class: monoclonal
Type: secondary
Antigen: rat alpha heavy chain
Host/Isotype : mouse/IgG1 kappa
Alpha heavy chain - MARA-2
Description : IgG1 kappa Mouse anti-rat alpha heavy chain
Class: monoclonal
Type: secondary
Antigen: rat alpha heavy chain
Host/Isotype : mouse/IgG1 kappa
Citations:
IgG1 kappa Mouse anti-rat epsilon heavy chain
Epsilon heavy chain - MARE-1
Description : IgG1 kappa Mouse anti-rat epsilon heavy chain
Class: monoclonal
Type: secondary
Antigen: rat epsilon heavy chain
Host/Isotype : mouse/IgG1 kappa
Citations:
- Studies on the mechanisms involved in antigen-evoked pleural inflammation in rats: contribution of IgE and complement.
- Characterisation of rat anti-guinea pig circulating xenoreactive natural antibodies and secreting cells.
- Differentiation of membrane IgE+ rat B cells into IgE-secreting cells.
- IgE and IgG2a antibody responses are induced by different antigen groups of the nematode Nippostrongylus brasiliensis in rats.
- IgG2b or IgE molecules can be co-expressed with those of the IgM and IgD isotypes of the membrane of normal rat B cells.
- Studies of the IgE binding sites to rat mast cell receptor with proteolytic fragments and with a monoclonal antibody directed against epsilon heavy chain: evidence that the combining sites are located in the C epsilon 3 domain.
- Nippostrongylus brasiliensis infection can induce IgE production in rnu/rnu rats.
IgG1 kappa Mouse anti-rat gamma heavy chain
Gamma heavy chain - MARG-1-1
Description : IgG1 kappa Mouse anti-rat gamma heavy chain
Class: monoclonal
Type: secondary
Antigen: rat gamma heavy chain
Host/Isotype : mouse/IgG1 kappa
IgG1 heavy chain - MARG-1-2
Description : IgG1 kappa Mouse anti-rat gamma heavy chain
Class: monoclonal
Type: secondary
Antigen: rat gamma heavy chain
Host/Isotype : mouse/IgG1 kappa
IgG1 kappa Mouse anti-rat IgG2a heavy chain
IgG2a heavy chain - MARG-2a-1
Description : IgG1 kappa Mouse anti-rat IgG2a heavy chain
Class: monoclonal
Type: secondary
Antigen: rat IgG1 heavy chain
Host/Isotype : mouse/IgG1 kappa
IgM kappa Mouse anti-rat IgG2a heavy chain
IgG2a heavy chain - MARG-2a-7
Description : IgM kappa Mouse anti-rat IgG2a heavy chain
Class: monoclonal
Type: secondary
Antigen: rat IgG2a heavy chain
Host/Isotype : mouse/IgM kappa
IgG1 kappa Mouse anti-rat IgG2b heavy chain
IgG2b heavy chain - MARG-2b-3
Description : IgG1 kappa Mouse anti-rat IgG2b heavy chain
Class: monoclonal
Type: secondary
Antigen: rat IgG2b heavy chain
Host/Isotype : mouse/IgG1 kappa
IgG2b heavy chain - MARG-2b-8
Description : IgG1 kappa Mouse anti-rat IgG2b heavy chain
Class: monoclonal
Type: secondary
Antigen: rat IgG2b heavy chain
Host/Isotype : mouse/IgG1 kappa
IgG2a kappa Mouse anti-rat IgG2c heavy chain
IgG2c heavy chain - MARG-2c-3
Description : IgG2a kappa Mouse anti-rat IgG2c heavy chain
Class: monoclonal
Type: secondary
Antigen: rat IgG2c heavy chain
Host/Isotype : mouse/IgG2a kappa
IgG2c heavy chain - MARG-2c-5
Description : IgG2a kappa Mouse anti-rat IgG2c heavy chain
Class: monoclonal
Type: secondary
Antigen: rat IgG2c heavy chain
Host/Isotype : mouse/IgG2a kappa
IgG2a kappa Mouse anti-rat IgG1, IgG2a, IgG2b, IgG2c
IgG1, IgG2a, IgG2b, IgG2c heavy chain - MARG-COC-1
Description : IgG2a kappa Mouse anti-rat IgG1, IgG2a, IgG2b, IgG2c
Class: monoclonal
Type: secondary
Antigen: rat IgG1, IgG2a, IgG2b, IgG2c heavy chain
Host/Isotype : mouse/IgG2a kappa
Citations:
- Accommodation of vascularized xenografts: expression of "protective genes" by donor endothelial cells in a host Th2 cytokine environment.
- Characterisation of rat anti-guinea pig circulating xenoreactive natural antibodies and secreting cells.
- Preformed antibody and complement rebound after plasma exchange: analysis of immunoglobulin isotypes and effect of splenectomy.
- In vivo depletion of xenoreactive natural antibodies with an anti-mu monoclonal antibody.
- Anti-renin T cells trigger normal B cells to produce anti-renin antibodies and normalize blood pressure in spontaneously hypertensive rats.
- IgE and IgG2a antibody responses are induced by different antigen groups of the nematode Nippostrongylus brasiliensis in rats.
- IgG2b or IgE molecules can be co-expressed with those of the IgM and IgD isotypes of the membrane of normal rat B cells.
- Isotype characterization of rat preformed natural antibodies against guinea pig cells
SYnAbs S.A.
Rue Auguste Piccard, 48
I-Tech Incubator 2
B-6041 Gosselies
Belgium
BE 0637.716.206
